The short answer, No.
There is no such thing as a truly Hypoallergenic Cat. In fact, touching a sphynx's bare skin can cause a serious allergic reaction. However, the lack of hair might keep the allergen from getting spread around the house. So, the Sphynx cat may be worth looking into for those willing to take certain precautions.
We have had some successes with introducing a Sphynx into families that have members with severe allergies to cats but we cannot guarantee it and unfortunately we do not allow visits from those looking to *test* it. We also have resident furry cats and would negate the test.
People with cat allergies are really allergic to proteins in the cat's saliva, urine, or dander (dried flakes of skin). While the Sphynx is a *hairless* breed, they do still create dander but it is not carried around on them as they do not have the fur to hold the dander in. As far as the saliva protein, Sphynx cats DO still lick and groom themselves leaving the protein on their skin.
We do recommend baths, and this may help with your allergies, however, we do have to mention that the more you bathe your sphynx, the more oils they will produce. These oils can leave brown stains on your furniture and bedding.